BDBM25770 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol::5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol, 5::Brethaire::Brethine::Bricanyl::Terbutaline::Terbutaline,(+/-)

SMILES CC(C)(C)NCC(O)c1cc(O)cc(O)c1

InChI Key InChIKey=XWTYSIMOBUGWOL-UHFFFAOYSA-N

Data  6 KI  5 IC50  10 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 25770   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKi:  2.51E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as intracellular cAMP accumulation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  3.98E+3nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  1.86E+3nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to human adrenergic beta2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  4.48E+3nMAssay Description:Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]-CGP12,177 from immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  2.40E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank